Autoimmune contraindications?

I have been working with psychedelics for a couple of years. About half the time guided and the other half solo. When I first met my guide we had the option of working with MDMA or mushrooms. Because I have Crohn's disease I was cautioned against MDMA. "It's hard on the body." However, any research I've done does not reference any issues with any kind of autoimmune disorder. The only thing I found was some early research that says it could be positive.

I have the opportunity to work in group session that uses MDMA first and then mushrooms. Does anyone have any experience or can reference any sources that say this is a bad idea?

Thanks in advance, you beautiful people.